Platelet-rich plasma (PRP) therapy utilizes an autologous blood fraction concentrated with platelets and bioactive growth factors to stimulate biological healing in degenerate cartilage, tendons, and ligaments.
Biological Mechanisms of Platelet Growth Factors
Centrifugation concentrates autologous platelets multi-fold above baseline. Upon joint delivery, alpha-granules discharge growth factors including PDGF, VEGF, and TGF-beta, activating local chondrocytes and tenocytes.
Common Clinical Indications
- Early-to-moderate knee and shoulder osteoarthritis
- Chronic tendinopathies including tennis elbow and Achilles tendonitis
- Partial-thickness meniscal tears and chondral defects
- Plantar fasciitis recalcitrant to physical therapy
Frequently Asked Questions
Are there allergy risks with autologous PRP?
Because the biological injectate is prepared purely from the patient's own peripheral blood, transmission and allergic rejection risks are completely eliminated.
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Key Orthopedic Treatments
Glossary Entries
- What is Achilles Tendinopathy?
- What is an Achilles Tendon Rupture?
- What is an Acromioclavicular Joint Separation?
- What is Ankylosing Spondylitis?
- What is the Anterior Cruciate Ligament (ACL)?
- What is an ACL (Anterior Cruciate Ligament) Tear?
- What is Arthroscopy?
- What is Articular Cartilage?
- What is Avascular Necrosis?
- What is a Baker's Cyst?
- What is Bursitis?
- What is Calcific Tendinitis of the Shoulder?
- What is Carpal Tunnel Syndrome?
- What is a Cervical Disc Herniation?
- What is Chondromalacia Patellae?
- What is Coxarthrosis (Hip Osteoarthritis)?
- What is Cubital Tunnel Syndrome (Ulnar Nerve Entrapment)?
- What is De Quervain's Tenosynovitis?
- What is Developmental Dysplasia of the Hip?
- What is a Joint Dislocation?
- What is a Distal Radius Fracture?
- What is Dupuytren Contracture?
- What is Ewing Sarcoma?
- What is a Femoral Neck Fracture?
- What is a Femoral Shaft Fracture?
- What is Femoroacetabular Impingement (FAI)?
- What is Fibromyalgia?
- What is Flatfoot (Pes Planus)?
- What is Frozen Shoulder (Adhesive Capsulitis)?
- What is a Ganglion Cyst?
- What is Golfer's Elbow (Medial Epicondylitis)?
- What is Gonarthrosis (Knee Osteoarthritis)?
- What is Gouty Arthritis and Hyperuricemia?
- What is Hallux Valgus (Bunion)?
- What is a Hammer Toe?
- What is a Hamstring Tear?
- What is Heel Spur and Plantar Fasciitis?
- What is a Hip Labral Tear?
- What is a Hyaluronic Acid Injection?
- What is a Joint?
- What is a Jones Fracture?
- What is Kinesio Taping?
- What is Kyphosis?
- What is a Ligament?
- What is a Lisfranc Injury?
- What is a Lumbar Disc Herniation (Slipped Disc)?
- What is Lumbar Spinal Stenosis?
- What is a Medial Collateral Ligament Injury?
- What is a Meniscus Tear?
- What is Mesotherapy in Orthopedics?
- What is Morton's Neuroma?
- What is Nerve Entrapment?
- What is Osgood-Schlatter Disease?
- What is Osteoporosis?
- What is Patellar Dislocation?
- What is Patellar Tendinopathy (Jumper's Knee)?
- What is Patellofemoral Pain Syndrome (Runner's Knee)?
- What is Peripheral Neuropathy?
- What is Perthes Disease?
- What is Piriformis Syndrome?
- What is Plantar Fasciitis?
- What is Prolotherapy?
- What is PRP (Platelet-Rich Plasma) Therapy in Orthopedics?
- What is Rheumatoid Arthritis?
- What is a Rotator Cuff Tear?
- What is a Scaphoid Fracture?
- What is a Scapholunate Ligament Injury?
- What is Sciatica?
- What is Scoliosis (Spinal Curvature)?
- What is Sesamoiditis?
- What is Shockwave Therapy (ESWT)?
- What is Shoulder Instability?
- What is the Skeletal System?
- What is a Soft Tissue Injury?
- What is Spondylolisthesis?
- What is a Sprain and Strain?
- What is Stem Cell Therapy in Orthopedics?
- What is a Stress Fracture?
- What is Subacromial Impingement Syndrome?
- What is Synovial Fluid?
- What is a Talus Fracture?
- What is Tarsal Tunnel Syndrome?
- What is a Tendon?
- What is Tennis Elbow (Lateral Epicondylitis)?
- What is Total Hip Replacement?
- What is Total Knee Arthroplasty (Knee Replacement)?
- What is Trigger Finger (Stenosing Tenosynovitis)?
- What is an Ulnar Collateral Ligament Injury?
- What is a Vertebra?
- What is a Vertebral Compression Fracture?
Related Treatments
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